A Stimulation Method to Assess the Contractile Status of the Lumbar Extensors in a Seated Posture

The purpose of present study was to develop and evaluate methods to assess stimulation responses of the lumbar extensors, as part of a longer‐term goal of detecting fatigue during prolonged sitting. Three stimulation frequencies (2, 5, and 8 Hz) were tested in separate stages, which include 3 stimulation trains and 4 sampling blocks. Repeated measures analyses of variance were used to determine whether any significant differences in mean stimulation responses occurred with respect to stimulation frequency, sampling block, and stimulation train. Reliability of measured stimulation responses was assessed within and between sampling blocks using intraclass correlation coefficients. Stimulation frequencies significantly affected the stimulation responses and time‐to‐potentiation differed between the 3 stimulation frequencies; it was highest for 2 Hz stimulation. All 3 stimulation frequencies resulted in excellent reliability within and between sampling blocks. Use of the current protocol at 2 Hz is recommended as appropriate to measure the lumbar extensors status during prolonged sitting.     

Improved synergetic excitation control for transient stability enhancement and voltage regulation of power systems

This paper proposes decentralized improved synergetic excitation controllers (ISEC) for synchronous generators to enhance transient stability and obtain satisfactory voltage regulation performance of power systems. Each generator is considered as a subsystem, for which an ISEC is designed. According to the control objectives, a manifold, which is a linear combination of the deviation of generator terminal voltage, rotor speed and active power, is chosen for the design of ISEC. Compared with the conventional synergetic excitation controller (CSEC), a parameter adaptation scheme is proposed for updating the controller parameter online in order to improve the transient stability and voltage regulation performance simultaneously under various operating conditions. Case studies are undertaken on a single-machine infinite-bus power system and a two-area four-machine power system, respectively. Simulation results show the ISEC can provide better damping and voltage regulation performance, compared with the CSEC without parameter adaptation scheme and the conventional power system stabilizer.     

Optimal Pricing Algorithm in the Electricity Market with Battery and Accumulator and Demand–Supply Balancing

This paper considers the day‐ahead market with batteries and accumulators to level power generation. First, we model consumers with batteries, generators with batteries, and accumulators, all of whom strive to maximize their own profit. An optimal pricing algorithm based on dual decomposition and the steepest descent method is derived and shown to be stable. Finally, the effectiveness of the algorithm is demonstrated by means of numerical simulations which indicate that it achieves demand–supply balance.     

On optimizing system energy of voltage–frequency island based 3-D multi-core SoCs under thermal constraints

Three dimensional (3-D) multi-core SoC has been recognized as a promising solution for implementing complex applications with lower system energy. Recently, voltage–frequency island (VFI)-based design paradigm was widely adopted for energy optimization. However, the existing work commonly targeted 2-D platform, which cannot handle the exacerbated thermal issues and the increased solution space from 3-D integration. In this paper, we propose an optimization framework targeting VFI-based 3-D multi-core SoCs to minimize system energy meanwhile still meeting task deadline and thermal constraints. Our framework conducts at an earlier design phase in which designers have the freedom to determine the core stacks and map them into the hardware platform. Besides energy-aware task scheduling, we also conduct core stacking and task adjusting to balance the powers across the chip for thermal optimization. Moreover, by treating each core stack as a unity, the complicated problem of core mapping and VFI partitioning in 3-D platform can be simplified as a 2-D one. Experimental results demonstrate that on average our framework can achieve an energy reduction of 15.8% over the prior thermal balancing algorithm [17] (X. Zhou, J. Yang, Y. Xu, et al. Thermal-aware task scheduling for 3D multicore processors, IEEE Trans. Parallel Distrib. Syst. (TPDS), 21(1) (2010), 60–71.). Moreover, on average a reduction of 4.8 °C in peak temperature is achieved by our framework, compared with the state-of-the-art energy optimization scheme [8] (U.Y. Ogras, R. Marculescu, P. Choudhary, et al. Voltage–frequency island partitioning for GALS-based networks-on-chip, in: ACM/IEEE Design Automation Conference (DAC), 2007, pp. 110–115.).     

杭州公共设施调研与分析——基于日常生活服务需求的视角

面对新形势下基本公共服务设施配置的新要求,杭州市开展了公共服务设施基本配套规定的评估与修订。有别于传统的"自上而下"制定各类设施配套标准的思路,此次评估与修订工作采用基于日常生活服务需求视角的"自下而上"的创新型思路,问卷与访谈相结合并将调研设施从公益性设施拓展到商业性设施,了解居民使用设施的频率、步行容忍时间等特征及对设施集中设置的意愿,以此为依据,对杭州市公共设施基本配套规定中设施类型的确定、设施功能的复合设置、服务半径的选取等方面提出建议。     

复频电导技术在隧洞超前探水中的应用

围岩富水带是隧道超前预报最关注的问题，目前，多使用电磁方法来预报围岩的含水性，但受到场地条件限制，面临掌子面条件、金属机具干扰、三维波场定位等诸多困难，特别是掌子面前方100 m范围内围岩的含水性预报，在国内外都是一个新的高难课题。在研究了岩体电导率与电容率复频特性的基础上，结合巴基斯坦NJ-TBM引水隧洞工程，开发了复频电导探水(CFC)技术。该技术基于电磁波反射与相干原理，选用100 kHz～10 MHz频率范围，采用电偶极子发射与阵列接收方式和偏移成像技术，突破了隧道内场地条件的限制。依据1/4相干波长确定含水体的位置，相干能量确定含水量的大小。在巴基斯坦NJ-TBM隧洞超前探水的应用，证明了该方法的可行性与有效性。      

Long Non-Coding RNAs as Master Regulators in Cardiovascular Diseases

Cardiovascular disease is the leading cause of death in the United States, accounting for nearly one in every seven deaths. Over the last decade, various targeted therapeutics have been introduced, but there has been no corresponding improvement in patient survival. Since the mortality rate of cardiovascular disease has not been significantly decreased, efforts have been made to understand the link between heart disease and novel therapeutic targets such as non-coding RNAs. Among multiple non-coding RNAs, long non-coding RNA (lncRNA) has emerged as a novel therapeutic in cardiovascular medicine. LncRNAs are endogenous RNAs that contain over 200 nucleotides and regulate gene expression. Recent studies suggest critical roles of lncRNAs in modulating the initiation and progression of cardiovascular diseases. For example, aberrant lncRNA expression has been associated with the pathogenesis of ischemic heart failure. In this article, we present a synopsis of recent discoveries that link the roles and molecular interactions of lncRNAs to cardiovascular diseases. Moreover, we describe the prevalence of circulating lncRNAs and assess their potential utilities as biomarkers for diagnosis and prognosis of heart disease.     

Using learning methodologies and resources in the development of critical thinking competency: An exploratory study in a virtual learning environment

This study aims to design and implement new learning methodologies and resources that seek to advance the development and assessment of one of the fundamental students’ competencies from any Business Administration Degree, such as critical thinking, that is, this is an exploratory study on computing for human learning, specifically, learning of key competencies for business. We are going to use audiovisual case methodology through the use of short film clips, usually real stories, to help students understand the practical implications of theoretical concepts explained in the classroom. A theoretical model test uses data from 32 business students from the Open University of Catalonia. The first results show positive attitudes toward a new technological resource ‘audio-visual cases’. They indicate that the use of this tool can improve the comprehension of a problem and its origins and, at the same time, stimulate learning. In addition, this tool helps to develop critical thinking competency. This study offers important contributions to an e-learning environment and their applicability to the workplace, since it is the first type of research about the impact of audiovisual cases in the acquisition of critical thinking competency. Furthermore, this methodology promotes collaborative learning.